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Chemical name: (6-(2-fluorophenyl)-1-methyl-8-nitro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine) . Molecular Formula: C17H12FN5O2
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Bromonordiazepam pellets with 2.5 milligrams of active substance
Synonym: Bromonordiazepam CAS Number: 2894-61-3 Formula: 7-bromo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Mole mass: 315.16464 Purity: >99%
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Synonym: Bromonordiazepam CAS Number: 2894-61-3 Formula: 7-bromo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Mole mass: 315.16464 Purity: >99%
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Formal Name – 6-(2-chlorophenyl)-1-methyl-8-nitro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
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Molecular Formula – C17H12ClN5O2
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Synonym: 2-ethyl-9-methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine CAS Number: 40054- 73-7 Formula: C17H16N4S Molar mass: 308.4 Purity: ≥ 99%
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Synonym: 2-ethyl-9-methyl-4-phenyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine CAS Number: 40054- 73-7 Formula: C17H16N4S Molar mass: 308.4 Purity: ≥ 99%
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Synonym: Flubromazepam CAS Number: 2647-50-9 Formula: 7- bromo- 5- (2- fluorophenyl)- 1,3- dihydro- 2H- 1,4- benzodiazepin- 2- one Molar mass: 333.2 g/mol Purity: >98%
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Synonym: Flubromazepam CAS Number: 2647-50-9 Formula: 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Mole mass: 333.2 g/mol Purity: >97%
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Fanax bars are no longer supplied. A replacement is Flubrotizolam Pellets. Synonym: 2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine CAS Number: 57801-95-3 Formula: C17H12BrFN4 Molar mass: 377.2 g/mol Purity: ≥99%
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Synonym: Flubrotizolam CAS Number: 57801-95-3 Formula: 4-bromo-7-(2-fluorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0 2,6 ] trideca-2(6),4,7,10,12-pentaene Molar mass: 377.24 g mol Purity: >98%
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  • Chemical Name: Fluclotizolam
  • Systematic Name: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
  • Molecular Formula: C17H12ClFN4
  • Molecular Weight: 326.76 g/mol
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What Are Benzodiazepines?

Benzodiazepines are a class of psychoactive drugs commonly prescribed for anxiety, insomnia, and other mental health disorders. They work by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, producing sedative, anxiolytic, and muscle-relaxant effects. This makes them valuable in treating conditions such as panic disorders, seizures, and insomnia.

What Are the Top 5 Benzodiazepines?

When it comes to the top 5 benzodiazepines, these are the most commonly prescribed:

  1. Diazepam (Valium): Widely used for anxiety, muscle spasms, and seizures.
  2. Alprazolam (Xanax): Commonly prescribed for anxiety and panic disorders.
  3. Clonazepam (Klonopin): Effective for panic disorders and certain types of seizures.
  4. Lorazepam (Ativan): Prescribed for anxiety disorders and as a pre-surgery sedative.
  5. Temazepam (Restoril): Often used for treating insomnia.

What Are the Side Effects of Benzodiazepines?

Common benzodiazepine side effects include drowsiness, dizziness, confusion, and impaired coordination. Long-term use can lead to dependence and withdrawal symptoms. It's crucial to understand these potential risks, especially when using benzodiazepines in research settings. Other side effects may include memory issues, fatigue, and in severe cases, respiratory depression.

What Are Benzodiazepines an Example Of?

Benzodiazepines are an example of central nervous system (CNS) depressants. They slow down brain activity, making them effective for treating anxiety, seizures, and sleep disorders. Their calming effects make them a significant area of interest in pharmacological research.

Is Benzodiazepine an Antidepressant?

No, benzodiazepines are not classified as antidepressants. While they are used to treat anxiety and insomnia, which can accompany depression, their primary function is to act as sedatives, not mood stabilizers or depression treatments. Antidepressants work differently by regulating serotonin and norepinephrine levels in the brain.

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Benzodiazepines List

Some common benzodiazepines include:

  • Diazepam (Valium)
  • Alprazolam (Xanax)
  • Lorazepam (Ativan)
  • Clonazepam (Klonopin)
  • Temazepam (Restoril)

These compounds are often studied for their effects on anxiety, seizures, and sleep disorders.

Benzodiazepines Side Effects

The side effects of benzodiazepines are well-documented. Short-term use may result in drowsiness, dizziness, and impaired coordination. Long-term use can lead to dependence, withdrawal symptoms, and increased risk of cognitive decline. It’s essential to monitor usage closely in research environments.

Benzodiazepines Mechanism of Action

Benzodiazepines work by enhancing the effect of GABA, a neurotransmitter that inhibits brain activity. This produces calming effects, making them useful for treating anxiety and seizure disorders. Their mechanism of action makes them a popular subject of pharmacological research.

Benzodiazepines Examples

Common benzodiazepine examples include Diazepam, Alprazolam, Lorazepam, and Clonazepam. These drugs are frequently prescribed for anxiety, panic disorders, and insomnia. They are also widely used in research to study their effects on the central nervous system.

Benzodiazepines Classification

Benzodiazepines fall under the classification of CNS depressants. They are a class of psychoactive drugs that reduce brain activity, making them useful in the treatment of anxiety, insomnia, and seizure disorders.

Benzodiazepines Effects

The primary effects of benzodiazepines include sedation, muscle relaxation, anxiety relief, and anticonvulsant properties. However, prolonged use can lead to tolerance, dependence, and withdrawal symptoms.

Benzodiazepines in English

Benzodiazepines are referred to by various names in different languages, but in English, they are known simply as "benzodiazepines" or "benzos." They are widely used in research due to their significant impact on brain function and mental health.

Benzodiazepines Addiction

Unfortunately, benzodiazepine addiction is a common risk with prolonged use. Dependence can develop quickly, making it essential for researchers to understand the addictive potential of these compounds when studying their effects.

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  • Anxiety Relief: Benzodiazepines are commonly used to alleviate symptoms of anxiety disorders, such as generalized anxiety disorder, panic disorder, and social anxiety disorder. Sedation and Sleep Aid: Some benzodiazepines have sedative properties, making them effective for treating insomnia and sleep disturbances.
  • Muscle Relaxation: Benzodiazepines can help relax skeletal muscles and provide relief from muscle spasms and tension.
  • Anticonvulsant Properties: Certain benzodiazepines are prescribed to manage seizures and prevent epileptic episodes.
  • Preoperative and Procedural Sedation: Benzodiazepines are sometimes administered before surgery or medical procedures to induce relaxation and reduce anxiety.

Popular Benzodiazepines:

  • Alprazolam (Xanax): Known for its anxiolytic properties, Alprazolam is often prescribed for generalized anxiety disorder and panic disorder.
  • Diazepam (Valium): Diazepam is a versatile benzodiazepine used to treat anxiety disorders, muscle spasms, and alcohol withdrawal symptoms.
  • Lorazepam (Ativan): Lorazepam is commonly prescribed for anxiety disorders, and insomnia, and as a preoperative sedative.
  • Clonazepam (Klonopin): Clonazepam is primarily used to manage seizures, panic disorder, and certain anxiety disorders.

Usage and Dosage: Dosage and administration instructions for Benzodiazepines vary depending on the specific medication and the individual's condition. It is crucial to follow the instructions provided by your healthcare professional or the product label. Always consult with a healthcare provider for accurate dosage recommendations.

  • Precautions and Warnings:
  • Prescription Only: Benzodiazepines are prescription medications and should only be used under the guidance of a healthcare professional.
  • Potential Side Effects: Common side effects of Benzodiazepines may include drowsiness, dizziness, impaired coordination, memory problems, and sedation. It's important to be aware of these effects and avoid activities that require alertness until you know how the medication affects you.
  • Dependency and Withdrawal: Benzodiazepines have the potential for dependency and withdrawal symptoms. Abrupt discontinuation or misuse can lead to withdrawal symptoms such as anxiety, insomnia, irritability, and seizures. Follow your healthcare provider's instructions for gradual dosage reduction if discontinuing the medication.
  • Drug Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions with Benzodiazepines.

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